Abstract:

To address the challenge of postoperative infections of spinal implants, a degradable regulatory composite coating was developed to achieve long-term and stable release of silver ions, combining excellent antibacterial effects, good biocompatibility, and osteogenic ability, providing a new research approach for the prevention and control of implant-related infections.

01Research Background

In the intervention scenarios of specific dislocation conditions in spinal surgery, the risk of postoperative infection is relatively high; traditional antibacterial implant coatings have problems with abnormal release rates, can only function for a short period, and may be accompanied by cytotoxicity, making it difficult to meet the application requirements of bone implants.

Original Source:

Journal: Bioactive Materials

Publication Date: 2026-02-27

DOI: 10.1016/j.bioactmat.2026.02.035

Authors: Kecheng Quan, Ting Zhang, Xingyu Zhou, Shanshan Liu, Zhinan Mao, Jiang Sun, Shilin Xue, Xingchen Yao, Yinglun Tian, Cheng Zhang, Jian He, Dingbang Xie, Weishi Li, Shenglin Wang, Yufeng Zheng, Nanfang Xu