The spread of COVID-19 worldwide has caused a major threat to human health. Although respiratory symptoms are a key feature of the disease, many people hospitalized for COVID-19 also suffer from acute kidney injury, which further exacerbates patient mortality. Therefore, when conditions permit, renal replacement therapy must be used to treat patients as much as possible. In addition, during the virus epidemic, the supply of dialysis treatment supplies including dialysate is also very tight. Therefore, there is an urgent need to develop materials that can effectively and quickly remove toxins from the body and restore electrolyte concentration.
Recently, Yury Gogotsi and others of Drexel University in the United States found that Ti3C2Tx MXene can effectively adsorb urea and can remove creatinine and uric acid from aqueous solutions and dialysates, with the maximum adsorption capacities of 45.7 and 17.0 mg/g, respectively. And they systematically analyzed and simulated the adsorption kinetics, isotherms and thermodynamics to determine the adsorption mechanism. In addition, they designed a fixed bed chromatography column equipped with Ti3C2Tx to further evaluate the adsorption performance under continuous fluid flow conditions and mirrored conditions in the form of continuous renal replacement therapy. In short, Ti3C2Tx has the potential to be used as an effective adsorbent for dialysate regeneration. It can accelerate dialysate regeneration by removing filtered toxins, and can promote more portable dialysis equipment, bringing good news to patients and the medical industry.

This work was published in the internationally renowned journal ACS Nano with the title "Adsorption of Uremic Toxins Using Ti3C2Tx MXene for Dialysate Regeneration" on August 24, 2020, DOI: 10.1021/acsnano.0c04546.

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